BrainKB

The open
neuroscience
knowledge graph.

Building open, trustworthy knowledge graph infrastructure to integrate fragmented neuroscience knowledge and data to accelerate reproducible discovery.

LiteratureDatasetsExperimentsDatabasesKnowledgeGraphEvidenceInsightsDiscovery

Key Features

Powerful tools for neuroscience knowledge extraction and management

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Ingest Knowledge Graphs

Easily upload neuroscience KGs in JSON-LD or TTL

Upload Knowledge Graph files in JSON-LD or Turtle format. Seamlessly integrate your neuroscience data into the BrainKB ecosystem.

NER Extraction

Extract neuroscience entities using AI agents

Extract Neuroscience Named Entities from text using multi-agent systems. Leverage advanced AI to identify and classify neuroscience concepts automatically.

Resource Extraction

Transform documents into structured knowledge

Extract structured resources from unstructured sources and documents. Transform raw text and PDFs into structured, queryable knowledge.

SynthScholar

PRISMA-guided literature reviews with AI

Run end-to-end PRISMA literature reviews — from search strategy to synthesis, screening, and critical appraisal — orchestrated across multiple LLMs.

What is BrainKB?

BrainKB is a platform designed to support neuroscience research by structuring and organizing scientific knowledge using knowledge graphs (KGs) for delivering evidence-based insights.

Structured Knowledge

BrainKB structures neuroscience knowledge into an accessible and scalable knowledge graph.

Data Exploration

It provides tools for searching, exploring, visualizing, and analyzing neuroscience data.

Community Contribution

Researchers can contribute new findings, represented as assertions with supporting evidence from publications.

Collaboration Hub

BrainKB aims to be the go-to resource for neuroscientists worldwide, fostering collaboration and accelerating discoveries.

Use Cases

BrainKB is actively developing use cases to support neuroscience research and knowledge management

Each use case includes ingestion, public view, and feedback components integrated with our Knowledge Graph

HMBA Taxonomy

Case 1

Hierarchical taxonomy management for neuroscience data classification and organization.

Ingestion process Public view & interactions Public feedback
View

Resources Extraction

Case 2

Extract and structure resources from unstructured documents and publications.

Ingestion process Public view & interactions Public feedback
View extracted resources

Resource Metadata Expansion

Case 3

Expand and enrich resource metadata including datasets with comprehensive information.

Ingestion process Public view & interactions Public feedback
In developmentView discussion

Neuroscientific Entity Extraction

Case 4

Extract and identify neuroscience entities from text using agentic AI.

Ingestion process Public view & interactions Public feedback
View extracted neuroscientific NER terms

Assertion Evidence

Case 5

Link scientific assertions with supporting evidence from publications and research.

Ingestion process Public view & interactions Public feedback
In developmentView discussion

SynthScholar

Case 6

PRISMA-guided literature review — search strategy, screening, critical appraisal, and synthesis orchestrated across multiple LLMs.

Ingestion process Public view & interactions Public feedback
View public reviews

Brain Visualization

Future Consideration

Connect all information through interactive brain visualization for comprehensive knowledge exploration.

Coming soon
Coming soon

About Use Cases

Each use case in BrainKB includes three key components that work together to create a comprehensive knowledge management system:

  • Ingestion Process: Data submission mechanisms (public or maintainer-only, depending on the use case)
  • Public View & Interactions: Accessible interfaces for exploring and interacting with the knowledge
  • Public Feedback: Community input and validation mechanisms

All use cases are integrated with (or are on a process of integration) the BrainKB Knowledge Graph, enabling seamless data flow and comprehensive knowledge representation.

View Full Planning Discussion

Structured Models

Structured models used in BrainKB.

Powered by Advanced AI Agents

BrainKB leverages cutting-edge agentic frameworks for structured information extraction. Our platform utilizes STRUCTSENSE, a task-agnostic agentic framework that enables sophisticated structured information extraction. SynthScholar extends this foundation to support PRISMA-guided literature synthesis, including structured data extraction and critical appraisal of scientific studies.

Research Citation:

Chhetri, T.R., Chen, Y., Trivedi, P., Jarecka, D., Haobsh, S., Ray, P., Ng, L. and Ghosh, S.S., 2025. STRUCTSENSE: A Task-Agnostic Agentic Framework for Structured Information Extraction with Human-In-The-Loop Evaluation and Benchmarking. arXiv preprint arXiv:2507.03674.

See Research Paper